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United States Government Accountability Office: 
GAO: 

Report to Congressional Requesters: 

May 2011: 

Managing Critical Isotopes: 

Weaknesses in DOE's Management of Helium-3 Delayed the Federal 
Response to a Critical Supply Shortage: 

GAO-11-472: 

GAO Highlights: 

Highlights of GAO-11-472, a report to congressional requesters. 

Why GAO Did This Study: 

Helium-3 gas is a key component of equipment used at ports and border 
crossings to detect radiation and prevent the smuggling of nuclear 
material into the United States, among other uses. The National 
Nuclear Security Administration (NNSA), a separate agency within the 
Department of Energy (DOE), extracts helium-3 and controls the 
inventory. Since 2003, NNSA has made helium-3 available for sale to 
DOE’s Isotope Development and Production for Research and Applications 
Program (Isotope Program). After September 11, 2001, demand increased 
for radiation detection equipment, and in 2008, the federal government 
learned that it faced a severe domestic shortage of the gas. GAO was 
asked to review DOE’s management of helium-3 to (1) determine the 
extent to which the federal government’s response to the helium-3 
shortage was affected by DOE’s management of helium-3; (2) determine 
the federal government’s priorities for allocating the limited supply 
of helium-3; and (3) describe the steps that the federal government is 
taking to increase the helium-3 supply and develop alternatives to 
helium-3. GAO reviewed DOE and NNSA documents and interviewed 
cognizant agency officials. 

What GAO Found: 

The federal government’s awareness of and response to the helium-3 
shortage was delayed because no DOE entity had stewardship 
responsibility for the overall management of helium-3—a by-product of 
the radioactive decay of tritium, a key component of the U.S. nuclear 
weapons program. Although the Isotope Program’s mission includes 
selling isotopes and providing related isotope services, senior 
program officials said that they interpret this mission to exclude 
helium-3 and 16 other isotopes that the program sells but whose supply 
it does not control. As a result of this weakness in DOE’s management 
of helium-3, officials at the Isotope Program and NNSA did not 
communicate about the helium-3 inventory or its extraction rate. 
According to NNSA and Isotope Program officials, they communicated 
with each other about how much helium-3 to sell each year and at what 
price but not about the size of the helium-3 inventory or extraction 
rate because NNSA generally treated this information as classified, 
due to concerns that the helium-3 inventory could be used to calculate 
the size of the U.S. tritium stockpile. NNSA and Isotope Program 
officials told GAO that this lack of communication contributed to the 
federal government’s delayed response to the helium-3 shortage. The 
standards for internal control in the federal government state that 
information should be communicated to management and others within a 
time frame that enables them to carry out their responsibilities. 
Further, without stewardship by a DOE entity, key risks to managing 
helium-3, such as the lack of complete information on the production 
and inventory of helium-3, were not identified or mitigated. The 
federal standards for internal control state that management should 
assess the risks faced from external and internal sources and decide 
what actions to take to mitigate them. 

Facing this critical shortage of helium-3, DOE and other federal 
agencies are collaborating to bring supply and demand into balance. 
Specifically, in July 2009, an interagency policy committee was 
formed, which halted allocations of helium-3 for domestic radiation 
detection equipment and established three priorities for allocating 
helium-3: (1) applications for which there are no alternatives to 
helium-3 have first priority (e.g., research that can be achieved only 
with helium-3); (2) programs for detecting nuclear material at foreign 
ports and borders have second priority; and (3) programs for which 
substantial costs have already been incurred have third priority 
(e.g., a DOE research facility that conducts physics research). 

To increase the supply of helium-3, the federal government is, among 
other things, pursuing other sources and developing alternatives. 
Specifically, NNSA is in discussions with Ontario Power Generation 
(OPG), a power company in Ontario, Canada, to obtain helium-3 from its 
stores of tritium. OPG has accumulated tritium as a by-product of 
producing electricity using a type of nuclear reactor not found in the 
United States. Also, federal agencies and private companies are 
researching alternative technologies to replace helium-3 in several 
applications to decrease demand. 

What GAO Recommends: 

GAO recommends, among other things, that DOE clarify whether the 
stewardship for those isotopes produced outside the Isotope Program, 
such as helium-3, rests with the program or another DOE entity. DOE 
stated that it understands and can implement these recommendations. 

View [hyperlink, http://www.gao.gov/products/GAO-11-472] for key 
components. For more information, contact Gene Aloise at (202) 512-
3841 or aloisee@gao.gov, or Timothy M. Persons at (202) 512-6412 or 
personst@gao.gov. 

[End of section] 

Contents: 

Letter: 

Scope and Methodology: 

Background: 

Federal Response to the Helium-3 Shortage Was Delayed by Weaknesses in 
DOE's Management of Helium-3: 

The Federal Government's Three Priorities for Allocating the Limited 
Supply of Helium-3 Exclude Domestic Radiation Detection Portal 
Monitors: 

Key Federal Agencies Are Collaborating to Increase the Helium-3 Supply 
and Develop Alternatives: 

Conclusions: 

Recommendations for Executive Action: 

Agency Comments and Our Evaluation: 

Appendix I: Comments from the Department of Energy: 

Appendix II: GAO Contacts and Staff Acknowledgments: 

Tables: 

Table 1: Quantities of Helium-3 Sold or Transferred from 2003 through 
2009: 

Table 2: Quantities of Helium-3 Allocated and Used, in Liters, from 
Fiscal Year 2009 to Fiscal Year 2011: 

Table 3: Allocated Helium-3 Prices per Liter: 

Figure: 

Figure 1: Helium-3 Request and Receipt Process: 

Abbreviations: 

cGMP: current good manufacturing practices: 

DHS: Department of Homeland Security: 

DOD: Department of Defense: 

DOE: Department of Energy: 

Isotope Program: Isotope Development and Production for Research and 
Applications Program: 

MOU: Memorandum of Understanding: 

NIH: National Institutes of Health: 

NIST: National Institute of Standards and Technology: 

NNSA: National Nuclear Security Administration: 

OPG: Ontario Power Generation: 

[End of section] 

United States Government Accountability Office: 
Washington, DC 20548: 

May 12, 2011: 

The Honorable Brad Miller: 
Ranking Member: 
Subcommittee on Energy and Environment: 
Committee on Science, Space, and Technology: 
House of Representatives: 

The Honorable Donna Edwards: 
Ranking Member: 
Subcommittee on Investigations and Oversight: 
Committee on Science, Space, and Technology: 
House of Representatives: 

Helium-3 gas is a critical component of radiation detection equipment, 
including radiation detection portal monitors that are used to screen 
cargo and vehicles at ports and border crossings around the world to 
prevent nuclear material from being smuggled into the United States. 
For example, the Department of Homeland Security (DHS) has deployed 
over 1,400 radiation detection portal monitors containing helium-3 at 
U.S. ports and border crossings. In addition, helium-3 is used in 
various industrial applications, such as oil and gas exploration and 
road construction, and in research applications, including physics 
research requiring ultra-low temperatures that can only be achieved 
using helium-3. Until 3 years ago, the United States' helium-3 supply 
was viewed as sufficient to meet demand. Outside the United States, 
Russia has been the only other major source of commercially available 
helium-3. But in 2008, the federal government abruptly learned that it 
faced a severe shortage of helium-3. At the same time Russia has 
curtailed its sales of helium-3, indicating that its supply is also 
waning. Because of this global shortage, no future deployments of 
radiation detection portal monitors containing helium-3 are planned in 
the United States. 

Helium-3 is a byproduct of the radioactive decay of tritium,[Footnote 
1] a key component of the nation's nuclear weapons that is used to 
enhance their power. The U.S. tritium stockpile is maintained by the 
National Nuclear Security Administration (NNSA), a separately 
organized agency within the Department of Energy (DOE).[Footnote 2] In 
maintaining this tritium stockpile, NNSA removes the helium-3 that 
accumulates as tritium decays because the helium-3 can diminish the 
effectiveness of the nuclear weapons. In the past, NNSA and its 
predecessor agencies considered helium-3 to be a waste product of the 
weapons program and vented it to the atmosphere. From about 1980 
through 1995, and again from 2003 through 2008,[Footnote 3] NNSA 
provided helium-3 to DOE's Isotope Development and Production for 
Research and Applications Program (Isotope Program) to sell. The 
Isotope Program's mission is to produce and sell isotopes and related 
isotope services, maintain the infrastructure required to do so, and 
conduct research and development on new and improved isotope 
production and processing techniques.[Footnote 4] DOE's Isotope 
Program produces and sells about 200 isotopes, though it does not 
control the supply--that is, the production or inventory--of all the 
isotopes it sells, such as helium-3, which is extracted from tritium 
by NNSA. 

With the end of the Cold War, the United States has been reducing the 
number of nuclear weapons in its stockpile, resulting in less tritium 
and, therefore, less helium-3. In the aftermath of the September 11, 
2001, terrorist attacks, however, demand for helium-3 increased due to 
the deployment of radiation detection portal monitors at ports and 
border crossings in the United States and other countries to prevent 
the smuggling of nuclear material. Thousands of such portal monitors 
were deployed across the United States and overseas, and more are 
planned to be deployed. Additionally, large quantities of helium-3 
have been used in the last 10 years by research facilities in the 
United States and internationally for large-scale physics research 
applications, and more is needed for this research to continue. 
Overall, this decreasing supply during a period of increasing demand 
resulted in a shortage of helium-3. 

In June 2008, a contractor alerted DHS that the contractor was unable 
to obtain a sufficient amount of helium-3 to fulfill its contract to 
provide radiation detection portal monitors. DHS contacted the Isotope 
Program to inquire about the helium-3 supply, and in September 2008, 
DOE responded to this sudden awareness of the shortage by suspending 
its helium-3 sales through public auction, which was the vehicle 
through which the Isotope Program sold helium-3. In March 2009, DHS, 
the Department of Defense (DOD), DOE, and NNSA formed an integrated 
project team to collect and analyze information and make 
recommendations to senior management at these departments on actions 
to be taken to address the shortage. The overall shortage of helium-3 
raises concerns about the United States' ability to provide a 
sustainable supply of helium-3 for national security and research 
applications. In this context, you asked us to review DOE's management 
of helium-3. Our objectives were to (1) determine the extent to which 
the federal government's response to the helium-3 shortage was 
affected by DOE's management of helium-3; (2) determine the federal 
government's priorities for allocating the limited supply of helium-3 
to various users; and (3) describe the steps that the federal 
government is taking, if any, to increase the helium-3 supply and 
develop alternatives to helium-3. 

Scope and Methodology: 

To determine the extent to which the federal government's response to 
the helium-3 shortage was affected by DOE's management of helium-3, we 
reviewed the DOE Isotope Program's strategic planning documents, 
helium-3 sales data, and information on NNSA's inventory of helium-3. 
We also interviewed officials at DOE, DOE's Savannah River Site, NNSA, 
and DHS, as well as representatives from Linde[Footnote 5] and GE 
Reuter-Stokes, the two principal companies that purchased helium-3 
from the Isotope Program. Also, we used the federal standards for 
internal control to assess DOE's management of helium-3.[Footnote 6] 
To determine the federal government's priorities for allocating the 
limited supply of helium-3 to various users, we reviewed documents of 
the integrated project team. We also reviewed the helium-3 allocation 
decisions, criteria, and process of the interagency policy committee 
convened in 2009 by the National Security Staff, which report to the 
National Security Advisor,[Footnote 7] to oversee the integrated 
project team and make policy decisions to manage the helium-3 
shortage. The policy committee is a multi-agency committee consisting 
of key agencies and departments that use helium-3 applications to 
support their missions, including the Department of Commerce's 
National Institute of Standards and Technology (NIST), DOD's Defense 
Threat Reduction Agency, the Department of State, DOE, and DHS. We 
also interviewed officials at NIST, the Department of Health and Human 
Services' National Institutes of Health (NIH), DHS, DOD, DOE, DOE's 
Oak Ridge and Pacific Northwest National Laboratories, and NNSA, as 
well as National Security Staff. To describe the steps that the 
federal government is taking, if any, to increase the helium-3 supply 
and develop alternatives to helium-3, we reviewed feasibility studies 
that presented options for alternative sources and recycling unused 
equipment and interviewed representatives from Ontario Power 
Generation, a Canadian power company. We reviewed research and 
documentation, including test results, on alternatives to helium-3 
that are being developed by companies and interviewed representatives 
from these companies and officials at DHS, DOD, DOE, NIH, NIST, NNSA, 
and Oak Ridge National and Pacific Northwest National Laboratories. We 
conducted this performance audit from April 2010 to May 2011, in 
accordance with generally accepted government auditing standards. 
Those standards require that we plan and perform the audit to obtain 
sufficient, appropriate evidence to provide a reasonable basis for our 
findings and conclusions based on our audit objectives. We believe 
that the evidence obtained provides a reasonable basis for our 
findings and conclusions based on our audit objectives. 

Background: 

The unique physical properties of helium-3 have led to its use in a 
wide variety of national security, scientific, industrial, and medical 
applications. Helium-3 is widely used for detecting nuclear material 
and safeguarding nuclear weapons because, among other things, of its 
ability to efficiently absorb neutrons. In radiation detection 
equipment, helium-3 is used to detect neutrons that are emitted by 
nuclear material. In radiation detection portal monitors, long, thin 
metal tubes are filled with helium-3; neutrons passing through these 
tubes react with the helium-3, creating charged particles that are 
detected by the monitors. Also, as a nontoxic gas that is not absorbed 
by the human body, helium-3 is used in magnetic resonance imaging 
(MRI) to research pulmonary disorders, such as chronic obstructive 
pulmonary disease.[Footnote 8] 

Helium-3 is rare because it is currently extracted solely as a 
byproduct of the radioactive decay of tritium. During the Cold War, 
the United States produced tritium in nuclear reactors and stockpiled 
it for the nuclear weapons program. Helium-3 is also available from 
natural sources, such as subterranean natural gas deposits, but it has 
not been pursued commercially in the past because it is found in very 
low concentrations. NNSA and its predecessor agencies produced tritium 
at the Savannah River Site K-reactor in South Carolina and purified 
tritium by removing helium-3 at the Mound Plant, a weapons research 
laboratory in Ohio. Following the end of the Cold War, as the United 
States reduced its nuclear weapons stockpile and ceased producing 
tritium, its inventory of helium-3 decreased commensurately. In 1988, 
DOE shut down the K-reactor for safety reasons and, in 1995, closed 
the Mound Plant, thus eliminating the U.S. government's large-scale 
ability to produce and purify tritium. NNSA has been able to meet the 
tritium needs of the nuclear weapons program by maintaining the 
existing stockpile and recycling tritium from dismantled nuclear 
warheads. 

To maintain the current tritium stockpile, NNSA extracts helium-3 from 
tritium on a daily basis and stores the helium-3 in pressurized 
cylinders at the Savannah River Site. To remove trace amounts of 
tritium and other impurities, NNSA ships these cylinders of helium-3 
to Linde in New Jersey, which operates the only commercial facility in 
the United States licensed by the Nuclear Regulatory Commission to 
purify helium-3 of trace amounts of tritium. While NNSA's helium-3 
inventory at the Savannah River Site is constantly changing, as of 
early February 2011, it was almost 31,000 liters. NNSA estimates that 
about 8,000 to 10,000 liters of helium-3 will be made available per 
year from the current tritium stockpile. Like the United States, 
Russia extracts helium-3 from its tritium stockpile. According to 
National Security Staff documentation and representatives of Linde, 
Russia has curtailed its sales of helium-3, indicating that its supply 
is likely waning. 

Isotope production and distribution has been a long-standing mission 
of DOE. DOE's Isotope Program provides isotopes to support the 
national need for a reliable supply of isotopes used in medicine, 
industry, and research. DOE transferred the Isotope Program to DOE's 
Office of Science from DOE's Office of Nuclear Energy starting in 
fiscal year 2009. In anticipation of this transfer, in August 2008, 
the Isotope Program organized a workshop to discuss the nation's needs 
for isotopes, and identified those isotopes with supply challenges. As 
noted in the workshop summary report, the workshop assembled, for the 
first time, stakeholders from all the different areas of the diverse 
isotope community to discuss the nation's current and future needs for 
isotopes and to consider options for improving the availability of 
needed isotopes.[Footnote 9] The workshop enabled the Isotope Program 
to discuss and develop program priorities, including those isotopes, 
such as helium-3, that were in short supply. This workshop identified 
12 isotopes, including helium-3, that faced supply challenges and had 
less than 3 years before their supplies at that time were completely 
consumed. 

In August 2003, the Isotope Program signed a Memorandum of 
Understanding (MOU) with NNSA to make available an initial 103,570 
liters of helium-3 for sale, followed by at least 10,000 liters of 
helium-3 per year from 2004 through 2008. At the time the MOU was 
signed, NNSA's inventory of helium-3 was estimated at about 260,000 
liters. Following this agreement, the Isotope Program held a series of 
public auctions to sell helium-3. A public auction process was used, 
according to program officials, to encourage competition. The Isotope 
Program and NNSA determined the quantity and minimum price of helium-3 
for each auction; the price was set to recover the costs to extract 
helium-3 and the administrative costs of selling it. Linde and GE 
Reuter-Stokes, a company that manufactures helium-3 tubes for 
radiation detection portal monitors and other neutron detection 
applications, have been the two buyers of helium-3 who participated in 
the Isotope Program's public auctions. From 2003 through 2009, the 
Isotope Program sold, or NNSA transferred, more than 209,000 liters of 
helium-3--an average of almost 30,000 liters of helium-3 per year, as 
shown in table 1. Given NNSA's capacity to extract between 8,000 and 
10,000 liters of helium-3 annually, this rate of sale exceeded the 
extraction rate and decreased the inventory. 

Table 1: Quantities of Helium-3 Sold or Transferred from 2003 through 
2009: 

Date sold: March 2003; 
Customer: Spectra Gases[A]; 
Quantity (liters): 7,826. 

Date sold: February 2004; 
Customer: G.E. Reuter-Stokes; 
Quantity (liters): 95,791. 

Date sold: June 2005; 
Customer: Spectra Gases[A]; 
Quantity (liters): 23,310. 

Date sold: July 2006; 
Customer: Spectra Gases[A]; 
Quantity (liters): 26,963. 

Date sold: August 2008; 
Customer: DOE Spallation Neutron Source (interagency transfer from 
NNSA); 
Quantity (liters): 34,325. 

Date sold: January 2009; 
Customer: Lind[E]; 
Quantity (liters): 10,585. 

Date sold: January 2009; 
Customer: G.E. Reuter-Stokes; 
Quantity (liters): 11,088. 

Total sold: 
Quantity (liters): 209,888. 

Source: GAO analysis of NNSA and Isotope Program data. 

[A] Spectra Gases was acquired by Linde in 2006 and changed its name 
to Linde in 2009. 

[End of table] 

Following the terrorist attacks of September 11, 2001, the demand for 
helium-3 nearly tripled, because of the increased focus on radiation 
detection applications. Specifically, DHS's Radiation Portal Monitor 
program, NNSA's Second Line of Defense program, and DOD's Guardian 
program all use helium-3 in radiation detection portal monitors 
deployed at domestic and foreign ports, border crossings, and military 
installations. DHS alone has deployed over 1,400 radiation detection 
portal monitors domestically. The largest demand for helium-3 has 
historically been for homeland security and scientific research, but 
demand for other applications, such as in MRIs for lung research, has 
also increased. 

Federal Response to the Helium-3 Shortage Was Delayed by Weaknesses in 
DOE's Management of Helium-3: 

The federal government's awareness of and response to the helium-3 
shortage was delayed because no DOE entity had stewardship 
responsibility for the overall management of helium-3. As a result of 
this lack of stewardship responsibility, officials from DOE's Isotope 
Program, which sold helium-3, and NNSA, which extracted it from 
tritium, did not communicate about the helium-3 inventory or its 
extraction rate. Without stewardship responsibility, key risks to 
managing helium-3, such as the lack of understanding of the helium-3 
inventory and the demand for helium-3, were not identified or 
mitigated by either entity. 

Officials from DOE's Isotope Program and NNSA Did Not Communicate 
about the Helium-3 Inventory or Its Extraction Rate: 

While the Isotope Program's mission includes selling isotopes and 
providing related isotope services, senior program officials said that 
they interpret this mission to exclude helium-3 and other isotopes 
that the program sells but whose supply it does not control. 
Accordingly, Isotope Program officials noted that the program sold and 
distributed helium-3 solely as a courtesy to NNSA, not because it was 
a core part of the program's mission or because it believed it had a 
stewardship responsibility to do so. NNSA officials also noted that 
helium-3 stewardship was not part of NNSA's mission of managing the 
nation's nuclear weapons. Without such stewardship responsibility, 
NNSA and Isotope Program officials did not communicate about the 
helium-3 inventory or its rate of extraction. 

The Isotope Program's management of helium-3 sales was hampered by 
this lack of communication regarding the size of the helium-3 
inventory and the rate at which helium-3 is extracted from tritium. 
Prior to selling helium-3 at public auction, officials from the 
Isotope Program and NNSA communicated with each other regarding how 
much helium-3 would be available to sell that year and the minimum 
price for which it would be sold at auction. However, Isotope Program 
and NNSA officials did not discuss the size of the helium-3 inventory, 
how much was being added to the inventory each year, or how quickly 
the inventory was being depleted. Additionally, NNSA officials did not 
inform Isotope Program officials when they transferred more than 
34,000 liters of helium-3 in August 2008 to DOE's Spallation Neutron 
Source, a physics research facility at the Oak Ridge National 
Laboratory that uses helium-3 in large-scale neutron detectors. This 
transfer--more than what the Isotope Program sold per year, on average 
from 2003 to 2009--greatly reduced the helium-3 inventory, but NNSA 
officials did not inform Isotope Program officials about it until 
after the transfer was completed. Despite the helium-3 inventory being 
greatly reduced, in September 2008 the Isotope Program and NNSA 
renewed their MOU to continue selling helium-3 for an additional 5 
years without discussing the size of the helium-3 inventory or the 
rate at which sales and large transfers--such as the one to DOE's 
Spallation Neutron Source--were reducing the inventory. 

Helium-3 inventory and production information was not shared between 
officials at the Isotope Program and NNSA because, according to NNSA 
officials, this information was generally treated as classified by 
NNSA out of concern that the inventory and annual extraction rate 
could be used to calculate the size of the U.S. tritium stockpile, 
which is classified. In describing the situation, Isotope Program 
officials stated that they did not have the requisite "need to know" 
to gain access to this information, and consequently, did not discuss 
it. In other words, Isotope Program officials did not believe that 
they needed complete information on the size of the helium-3 inventory 
or how much was being added to the inventory each year in order to 
carry out the program's mission because helium-3 does not fall within 
its mission. One of the standards for internal control in the federal 
government--information and communications--states that information 
should be recorded and communicated to management and others within an 
entity in a form and within a time frame that enables them to carry 
out their responsibilities.[Footnote 10] The lack of communication 
between NNSA and Isotope Program officials was not consistent with 
this standard. Isotope Program and NNSA officials told us that this 
lack of communication contributed to the government's delayed response 
to the helium-3 shortage. NNSA officials acknowledged the ambiguity 
about what information can be communicated about the helium-3 
inventory and, in January 2010, issued a memorandum to clarify and 
broaden what information about helium-3 can be shared publicly. As a 
result, NNSA now reports that 8,000 to 10,000 liters of helium-3 will 
be made available per year. 

Without Stewardship Responsibility, Key Risks to Managing Helium-3 
Were Not Identified or Mitigated: 

Senior Isotope Program officials said that they did not identify and 
mitigate key risks to managing helium-3 sales because, unlike most 
isotopes that the program sells, officials do not consider stewardship 
of helium-3 to be part of the program's mission. Specifically, these 
Isotope Program officials did not consider their lack of understanding 
of the helium-3 inventory or the demand for helium-3 as risks to 
managing helium-3 sales. According to these officials, for those 
isotopes that are included in its mission--the isotopes that it 
produces--the Isotope Program developed strategic planning documents 
and generally updated these documents on an annual basis. We reviewed 
the Isotope Program's strategic planning documents and found examples 
where the program assessed risks to isotopes that it produces and 
sells. The Isotope Program, however, did not perform strategic 
planning for helium-3, including assessing risks, because program 
officials do not consider stewardship of helium-3 to be part of the 
program's mission. For those isotopes that the Isotope Program sells 
but whose supply it does not control, such as helium-3, Isotope 
Program officials told us that they see their role as a conduit that 
sells these isotopes to customers as a courtesy. There are 17 
isotopes, including helium-3, that the program sells but, according to 
program officials, does not have stewardship responsibility for 
because the Isotope Program does not control their supply. For 
example, lithium-6, which is used in neutron detection applications 
and battery research, is sold by the Isotope Program, but its supply 
is controlled by NNSA. 

Although program officials do not consider helium-3 to be part of the 
program's mission, it nonetheless collected information in order to 
forecast demand. To do this, the Isotope Program recorded the number 
of telephone inquiries from potential customers and the volume of 
helium-3 discussed. Because it does not view helium-3 as a part of its 
mission, program officials said that the Isotope Program did not take 
proactive steps to solicit information to better understand future 
demand. For example, according to representatives, the Isotope Program 
did not solicit information from Linde, the company that had purchased 
or purified nearly all the helium-3 in the United States, which gave 
Linde a more complete understanding of the historical and future 
demand for helium-3. In tracking telephone inquiries, the Isotope 
Program's records show that it received nine telephone calls in 2008 
from customers who were interested in acquiring 1,226 liters of helium-
3. In contrast, according to Linde documentation, based on its actual 
use, the demand for helium-3 in 2008 was nearly 60,000 liters. Linde 
representatives also noted that the Isotope Program did not seek 
demand-related information from Linde until after the shortage was 
realized. 

Isotope Program officials told us that forecasting the demand for 
isotopes is very difficult because demand for isotopes can quickly 
change. Because of its effect on isotope inventories, changing demand 
is a risk to the program's management of the sale of all isotopes. One 
of the federal standards for internal control--risk assessment--states 
that management should assess the risks faced entity-wide, and at the 
activity level, from both external and internal sources, and that once 
risks have been identified, management should decide what actions 
should be taken to mitigate them. Risk identification methods may 
include, among other things, forecasting and strategic planning, and 
consideration of findings from audits and other assessments. A DOE 
advisory committee has also noted the importance of understanding 
demand for isotopes. In August 2008, DOE tasked its Nuclear Science 
Advisory Committee with establishing a standing subcommittee to 
research the needs and challenges of the Isotope Program and make 
recommendations to address them. According to the subcommittee report, 
for the Isotope Program to be efficient and effective, it is essential 
that it accurately forecasts the demand for isotopes.[Footnote 11] The 
report noted that the "ability of the program to predict demand for 
certain isotopes needs vast improvement." It went on to recommend that 
the program "maintain a continuous dialogue with all interested 
federal agencies and commercial isotope customers to forecast and 
match realistic isotope demand and achievable production capabilities." 

Isotope Program officials told us that they are considering convening 
a workshop, possibly in the summer of 2011, with federal agency 
stakeholders to discuss supply and demand of all isotopes that are 
produced or sold by the Isotope Program. According to the Director of 
the Facilities and Project Management Division, which manages the 
Isotope Program, while the program does not consider this role a part 
of its mission, it is volunteering to convene this workshop to be 
helpful to the isotope user community. 

The Federal Government's Three Priorities for Allocating the Limited 
Supply of Helium-3 Exclude Domestic Radiation Detection Portal 
Monitors: 

In July 2009, the National Security Staff, under the National Security 
Advisor, established an interagency policy committee consisting of 
officials from DOD, DOE, DHS, the Department of Commerce, and the 
Department of State to address the helium-3 shortage. In doing so, the 
policy committee established the following three priorities for 
allocating the limited supply of helium-3: 

* Priority 1: Applications for which there are no alternatives to 
helium-3, which includes, for example, research that requires ultra-
low temperatures that can be achieved only with helium-3. 

* Priority 2: Programs for detecting nuclear material at foreign ports 
and borders, which includes, for example, NNSA's Second Line of 
Defense program that deploys radiation detection portal monitors at 
key overseas ports and border crossings. 

* Priority 3: Programs for which substantial costs have already been 
incurred, such as DOE's Spallation Neutron Source research facility 
that conducts physics research. 

Furthermore, the committee eliminated further allocations of helium-3 
for domestic radiation detection portal monitors beginning in fiscal 
year 2010 because, according to committee documents, it determined 
there are alternatives to using helium-3 to detect neutrons in these 
portal monitors. The policy committee also determined that it will not 
support allocating helium-3 for any new applications that would 
increase the demand for helium-3. 

Following this approach, the policy committee has allocated helium-3 
to federal agency and commercial customers from 2009 through 2011, as 
shown in table 2. These allocations have brought the supply and demand 
of helium-3 into closer balance and mark a significant decrease from 
the amount the Isotope Program previously sold or transferred from 
2003 through 2009--an average of about 30,000 liters per year. 

Table 2: Quantities of Helium-3 Allocated and Used, in Liters, from 
Fiscal Year 2009 to Fiscal Year 2011: 

Customer: Low temperature research; 
Quantities: FY 2009: N/A[A]; 
Quantities: FY 2010: 452[B]; 
Quantities: FY 2011: 700. 

Customer: DHS; 
Quantities: FY 2009: N/A[A]; 
Quantities: FY 2010: 438[C]; 
Quantities: FY 2011: 1,218. 

Customer: DOD; 
Quantities: FY 2009: N/A[A]; 
Quantities: FY 2010: 1,530; 
Quantities: FY 2011: 3,521. 

Customer: NNSA; 
Quantities: FY 2009: 6,367; 
Quantities: FY 2010: 5,098[D]; 
Quantities: FY 2011: 5,791. 

Customer: DOE's Office of Science; 
Quantities: FY 2009: 2,400; 
Quantities: FY 2010: 341; 
Quantities: FY 2011: 315. 

Customer: Intelligence Community; 
Quantities: FY 2009: N/A[A]; 
Quantities: FY 2010: N/A[A]; 
Quantities: FY 2011: 763. 

Customer: NIH; 
Quantities: FY 2009: N/A[A]; 
Quantities: FY 2010: 260[E]; 
Quantities: FY 2011: 1,400. 

Customer: NIST; 
Quantities: FY 2009: N/A[A]; 
Quantities: FY 2010: 607[F]; 
Quantities: FY 2011: 236. 

Customer: Oil and gas industry; 
Quantities: FY 2009: N/A[A]; 
Quantities: FY 2010: 695[G]; 
Quantities: FY 2011: 1,000. 

Customer: Road construction industry; 
Quantities: FY 2009: N/A[A]; 
Quantities: FY 2010: N/A[A]; 
Quantities: FY 2011: 350. 

Customer: Total; 
Quantities: FY 2009: 8,767; 
Quantities: FY 2010: 9,421; 
Quantities: FY 2011: 15,294. 

Source: GAO analysis of information from the interagency policy 
committee and Linde. 

[A] N/A refers to instances when a customer either did not receive an 
allocation or received its allocation through another customer. 

[B] Low temperature research was allocated 1,800 liters but used only 
452 liters. 

[C] DHS was allocated 772 liters but used only 438 liters. 

[D] NNSA was allocated 5,150 liters but used only 5,098 liters. 

[E] NIH was allocated 1,800 liters but used only 260 liters. 

[F] NIST was allocated 832 liters but used only 607 liters. 

[G] The oil and gas industry was allocated 1,000 liters but used only 
695 liters. 

[End of table] 

The policy committee developed a process for customers to request 
allocations of helium-3 using "champions," which are agency officials 
who represent the federal agencies for which they work and its 
grantees; a champion is appointed by the Isotope Program for 
nonfederal customers, such as the oil and gas industry. The champion 
for a specific category of customer gathers all the helium-3 requests 
and determines whether the requests are consistent with the policy for 
allocating helium-3. If so, the champion submits the requests to the 
policy committee. The policy committee weighs the requests against the 
helium-3 priorities and the amount of helium-3 that is available to 
make allocation decisions. After allocation decisions are made, 
customers are notified and, if they received an allotment, they must 
submit a request for the helium-3 to Linde, which is contracted by the 
Isotope Program to purify and distribute the helium-3 allocations. 
When Linde receives a request for helium-3, according to Linde 
representatives, they verify the customer's allocation with the 
appropriate champion. Once verification is received, Linde ships the 
allotted amount of helium-3 to the customer. This allocation and 
receipt process is the same for all customers--federal agencies, 
researchers, and private companies, as shown in figure 1. 

Figure 1: Helium-3 Request and Receipt Process: 

[Refer to PDF for image: process illustration] 

Requesting Annual Helium-3 Allocations: 

1) Helium-3 customer submits request to champion. 

2) Champion determines whether request meets policy: 
Request rejected: Customers may resubmit their helium-3 requests to 
the champion the following year. 

3) Request approved. 

4) Champion submits request to policy committee. 

5) Policy committee reviews helium-3 request: 
Request rejected: Customers may resubmit their helium-3 requests to 
the champion the following year. 

6) Request approved. 

Receiving Annual Helium-3 Allocations: 

7) Helium-3 customer submits request to Linde. 

8) Linde verifies request with appropriate champion. 

9) Allocation of helium-3 verified by champion. 

10) Linde ships helium-3 to customer. 

Source: GAO analysis of information from DOE and Linde. 

[End of figure] 

The helium-3 champions or the policy committee may reject a request 
for helium-3, as shown in figure 1. If rejected, customers may 
resubmit a request the following year. According to seven of the 
agency champions, customers are aware of the policy committee's 
priorities and have usually reduced the amount of their request to the 
absolute minimum amount of helium-3 that is needed. As a result, the 
committee has approved most requests. 

When determining the annual allocations for helium-3, the policy 
committee also recommends to the Isotope Program a price at which 
helium-3 should be sold to different customers--including the federal, 
medical, and commercial entities. When the policy committee first 
began to allocate helium-3 in 2009, the Isotope Program, in 
consultation with the policy committee, established two different 
prices--one for medical applications and the other for all other 
applications. For use in the manufacture of drugs, medical devices, 
and other products, the Food and Drug Administration requires that 
helium-3 must be certified to meet specific requirements, called 
current good manufacturing practices (cGMP).[Footnote 12] In 2009, the 
price for cGMP helium-3 was $600 per liter; helium-3 for all other 
applications was priced at $450 per liter.[Footnote 13] Certifying 
helium-3 under cGMP requirements is more expensive, according to Linde 
representatives, because of the extra certification and purity testing 
that is required. This practice was continued for allocations in 2010. 
In 2011, however, the Isotope Program divided the price for helium-3 
to be used for non-cGMP applications into two categories: one for 
federal agencies and their grantees and one for commercial and 
nonfederal agencies. Table 3 shows the different prices for helium-3, 
per liter, beginning with 2009. 

Table 3: Allocated Helium-3 Prices per Liter: 

Customer: Federal agencies and their grantees; 
2009: $450; 
2010: $365; 
2011: $600. 

Customer: Commercial and nonfederal agencies; 
2009: $450; 
2010: $365; 
2011: $1,000. 

Customer: cGMP; 
2009: $600; 
2010: $485; 
2011: $720. 

Source: GAO analysis of information from DOE and Linde. 

[End of table] 

Key Federal Agencies Are Collaborating to Increase the Helium-3 Supply 
and Develop Alternatives: 

DOE and NNSA are taking actions to increase the supply of helium-3 by, 
among other things, pursuing other sources and recycling helium-3 from 
retired equipment. Specifically, NNSA officials said that NNSA is in 
discussions with Ontario Power Generation (OPG) to determine the 
feasibility of obtaining helium-3 from OPG's stores of tritium. OPG 
has accumulated this tritium as a by-product of producing electricity 
using heavy-water nuclear reactors.[Footnote 14] According to OPG 
officials, it owns 16 heavy-water nuclear reactors that are currently 
operating that have produced enough tritium to initially yield 
approximately 100,000 liters of helium-3. According to NNSA officials, 
once this initial amount is recovered, OPG estimates that its stores 
of tritium may yield about 10,000 liters of helium-3 annually. 
Combined with NNSA's current annual production of helium-3, obtaining 
helium-3 from OPG could boost the United States' supply to about 
18,000 to 20,000 liters per year. In addition, DHS and DOE have 
expressed interest in exploring the option of extracting helium-3 from 
natural helium, or helium-4. Helium-3 is found in small quantities in 
natural helium and could possibly be extracted from the nation's 
helium reserve near Amarillo, Texas, that is managed by the Department 
of the Interior's Bureau of Land Management. The Bureau of Land 
Management estimates that approximately 125,000 liters of helium-3 may 
be present in the helium reserve, which could be extracted over the 
next 10 years. DOE officials estimate that a similar reserve of 
natural helium in Wyoming could yield another 200,000 liters of helium-
3 that could be extracted over the life of the reserve. DHS officials 
note, however, that a feasibility study is needed to determine whether 
it would be cost-effective to extract helium-3 from natural helium. 

Federal agencies and private sector companies have started to recycle 
helium-3 from unused equipment in order to boost the supply. For 
example, an analysis conducted by DOE shows that it can extract helium-
3 from retired tritium storage beds at its tritium extraction facility 
at the Savannah River Site. DOE estimates that it could extract 8,000 
to 10,000 liters from these storage beds every 8 to 10 years, 
beginning as early as 2012. Additionally, DOE surveyed its national 
laboratories and identified over 1,500 liters of helium-3 in unused 
equipment and storage cylinders that could be reused immediately. DHS 
has also identified retired equipment from which helium-3 can be 
extracted. Private companies have also started to recycle helium-3 
from decommissioned radiation detection portal monitors. For example, 
according to a representative from a helium-3 tube manufacturing 
company, the company is buying retired radiation detection equipment 
to extract the helium-3. 

In addition to increasing the supply of helium-3, federal agencies and 
private companies are researching alternatives to helium-3 for several 
applications in order to decrease demand. For example, the government 
is conducting research to develop alternatives for neutron detection 
applications, including radiation detection portal monitors and 
nuclear physics research, which together use more helium-3 than any 
other application. DHS, DOE, DOD, and NIST, for example, are 
supporting approximately 30 different programs, some of which may 
result in technologies available for use in radiation detectors that, 
according to agency documents, could be ready by 2012.[Footnote 15] 
Similarly, DOE's Spallation Neutron Source research facility is 
coordinating with similar facilities internationally--including those 
in Germany, Japan, Russia, and Sweden--to develop alternative 
technologies for large-scale physics research applications. The 
private sector is also researching alternatives to helium-3 for 
radiation detection portal monitors and other applications, including 
MRIs for the lungs. For example, equipment using the isotopes lithium-
6 and boron-10 may be able to replace helium-3 in radiation detection 
portal monitors, according to representatives from companies that are 
developing them. Like helium-3, lithium-6 is produced by NNSA and sold 
by the Isotope Program. According to one program official, this 
official contacted NNSA to inquire about the inventory and production 
rate of lithium-6 because of the potential for increased demand if 
lithium-6-related technologies are chosen to replace helium-3 in 
radiation detection portal monitors. NNSA officials told the Isotope 
Program official, however, that such information is classified and 
cannot be shared, but assured the official that NNSA has enough 
lithium-6 to meet any future increase in demand. In March 2011, the 
Director of the Facilities and Project Management Division, which 
manages the Isotope Program, said that, although classified, program 
officials do have access to this information through NNSA's Office of 
Nuclear Materials Integration. DOE officials said that they have 
evaluated the potential demand for lithium-6 and have taken steps to 
ensure there is an adequate supply. According to its director, the 
Office of Nuclear Materials Integration is responsible for, among 
other things, coordinating management of certain isotopes produced by 
NNSA, including tracking the inventory of these isotopes, and 
coordinating communication within DOE and NNSA. The director stated 
that it is the responsibility of the Isotope Program, however, to 
manage the activities under its control for these isotopes, such as 
selling them outside DOE and NNSA and conducting 5-year supply and 
demand forecasts. This raises concerns that without stewardship 
responsibility for the overall management of the supply and demand of 
lithium-6, or the other isotopes produced by NNSA, neither the Isotope 
Program nor any other DOE or NNSA entity may detect an imbalance, 
resulting in the shortage of another isotope. 

Conclusions: 

Facing a critical shortage of helium-3 since 2008, DOE and other 
federal agencies are collaborating to bring supply and demand into 
balance, while supporting essential applications for which there are 
no alternatives. This shortage occurred because the demand for helium-
3 rose sharply in response to the increased deployment of radiation 
detection portal monitors, in addition to the increased use of helium- 
3 in research and other applications. The amount of helium-3 sold by 
the Isotope Program quickly outpaced the annual production, and this 
imbalance went undetected until the supply of helium-3 reached a 
critical shortage. The overall federal awareness of and response to 
the helium-3 shortage was delayed because no entity within DOE had 
stewardship responsibility for coordinating the production and sale of 
helium-3. Furthermore, there was a lack of communication between NNSA 
and Isotope Program officials over the size of the helium-3 inventory, 
how much was added to the inventory annually, and how quickly the 
Isotope Program's sales were depleting the inventory. While the 
Isotope Program's mission is to manage the production and sale of 
isotopes, including developing strategic plans and assessing risks for 
these isotopes, it has not taken a similar stewardship role in 
managing the 17 isotopes, including helium-3, whose supply it does not 
control. A key risk to managing the sale of all these isotopes is the 
lack of control over, and knowledge of, their supply. Under the 
federal standards for internal control, federal managers are to assess 
the risks faced entity-wide, and at the activity level, from external 
and internal sources and decide what actions to take to mitigate such 
risks. Because Isotope Program officials do not believe that they have 
a stewardship role for helium-3, they did not take steps to mitigate 
the risk of selling helium-3 without information on the size of the 
inventory or its rate of replenishment. Similarly, without a 
stewardship role, the program did not take sufficient steps to 
accurately forecast the increased demand for helium-3. Such 
forecasting is important in order to align demand with current 
inventory levels. In this regard, the subcommittee report of the 
Nuclear Science Advisory Committee stated that for the Isotope Program 
to be efficient and effective, it needs accurate forecasts for the 
demand for isotopes. A lack of communication and failure to identify 
risks and forecast demand ultimately delayed the Isotope Program's 
awareness of, and the federal government's response to, the helium-3 
shortage. In conclusion, we believe that all isotopes without clear 
stewardship responsibilities may face the same risks that led to the 
helium-3 shortage. 

Recommendations for Executive Action: 

We are making four recommendations to the Secretary of Energy designed 
to avoid future shortages associated with managing all isotopes that 
the Isotope Program sells but whose supply it does not control, 
including helium-3. First, we recommend that the Secretary of Energy 
clarify whether the stewardship for all these isotopes belongs with 
the Isotope Program or elsewhere within the Department of Energy. Once 
the stewardship for these isotopes has been assigned, we further 
recommend that the Secretary of Energy direct the head of the 
responsible office(s) to take the following three actions: 

* develop and implement a communication process that provides complete 
information to the assigned entity on the production and inventory of 
isotopes that are produced outside the Isotope Program; 

* develop strategic plans that, among other things, systematically 
assess and document risks to managing the isotopes and supporting 
activities, such as not having control over the supply of these 
isotopes, and implement actions needed to mitigate them; and: 

* develop and implement a method for forecasting the demand of 
isotopes that is more accurate than the one that is currently used. In 
this regard, the actions taken should be consistent with the 
forecasting recommendation from the subcommittee report of the Nuclear 
Science Advisory Committee. 

Agency Comments and Our Evaluation: 

We provided a draft of this report to the Secretaries of Energy and 
Homeland Security for their review and comment. DHS had no comments on 
the findings of the draft report or our recommendations. In a written 
response for DOE, the National Nuclear Security Administration's 
Associate Administrator for Management and Budget stated that he 
understands our recommendations and can implement them but took 
exception to our characterization of the Isotope Program's mission. In 
the report, we state that the Isotope Program's mission is to produce 
and sell isotopes and related isotope services, maintain the 
infrastructure required to do so, and conduct research and development 
on new and improved isotope production and processing techniques, 
which was its mission from 2003 through 2008--the time during which 
the Isotope Program was selling helium-3 by auction and the helium-3 
shortage occurred. In its response, NNSA explained that the Isotope 
Program has been working to clarify its responsibilities for isotopes 
since 2009. In this regard, the DOE fiscal year 2012 Congressional 
Budget request describes the Isotope Program's mission as that of 
producing and distributing isotopes that are not commercially 
available and distributing other materials as a service to DOE. 
However, according to NNSA's comments, the Isotope Program does not 
have the mission to be the steward of stockpiles of other materials 
and their byproducts, including helium-3. Neither DOE's fiscal year 
2012 Congressional Budget request, nor NNSA's comments explain what 
entity does have stewardship responsibility for helium-3 and several 
other isotopes that are sold by the Isotope Program, but produced 
elsewhere. Regardless of how the Isotope Program defines its mission 
today, at the most crucial time when helium-3 should have been 
carefully managed in order to avoid the sudden awareness of the 
shortage, no one entity believed it had the responsibility to do so. 
As a result, the shortage of an isotope that is critical to national 
security, research, industrial, and medical applications went 
undetected until the supply reached a critical level. Our 
recommendations are intended to assist in avoiding such a problem with 
helium-3 and other isotopes in the future. 

DOE also provided technical comments that we incorporated as 
appropriate throughout the report. DOE's comments on our draft report 
are included in appendix I. 

As agreed with your offices, unless you publicly announce the contents 
of this report earlier, we plan no further distribution until 30 days 
from the report date. At that time, we will send copies to the 
appropriate congressional committees, Secretaries of Energy and 
Homeland Security, Administrator of NNSA, National Security Staff, and 
other interested parties. The report will also be available at no 
charge on the GAO Web site at [hyperlink, http://www.gao.gov]. 

If you or your staffs have any questions about this report, please 
contact Gene Aloise at (202) 512-3841 or aloisee@gao.gov or Timothy M. 
Persons at (202) 512-6412 or personst@gao.gov. Contact points for our 
Offices of Congressional Relations and Public Affairs may be found on 
the last page of this report. GAO staff who made key contributions to 
this report are listed in appendix II. 

Signed by: 

Gene Aloise: 
Director: 
Natural Resources and Environment: 

Signed by: 

Timothy M. Persons, Ph.D. 
Chief Scientist: 
Director, Center for Science, Technology, and Engineering: 

[End of section] 

Appendix I: Comments from the Department of Energy: 

NNSA: 
Department of Energy: 
National Nuclear Security Administration: 
Washington, DC 20585: 

May 4,	2011: 
Mr. Gene Aloise: 
Director: 
Natural Resources and Environment: 
Government Accountability Office: 
Washington. DC: 20458: 

Dear Mr. Aloise: 

The Department or Energy (Department) and National Nuclear Security 
Administration (NNSA) appreciates the opportunity to review the 
Government Accountability Office's (GAO) report, Managing Critical 
Isotopes: Weaknesses in DOE's Management of Helium-3 Delayed the 
Federal Response to a Critical Supply Shortage, GAO-11-472. In 
response to a request made by the Subcommittee on Investigations and 
Oversight, Committee on Science and Technology, House of 
Representatives. GAO was asked to review the Department of
Energy's (DOE) management of He-3 to: (1) determine the extent to 
which the federal government's response to the He-3 shortage was 
affected by DOE's management of He-3; (2) determine the federal 
government's priorities for allocating the limited supply of
He-3; and (3) describe the steps that the federal government is taking 
to increase the He-3 supply and develop alternatives to He-3. NNSA is 
responding on behalf or the Department. 

The Department recognizes the need for improvements in managing He-3 
and began to address this issue in 2008 via the Integrated Product 
Team (Team). As described in this report, He-3 allocation priorities 
have been established that have brought the supply and demand into a 
better balance. The result has been to defer the total exhaustion of 
US-origin He-3 from 2011 until the 2017-2018 timeframe, allowing the 
Team to develop alternative technologies to reduce the need for He-3, 
as well as secure additional supply. 

We understand the GAO recommendations and can implement them. We are 
concerned, however, that the report does not accurately reflect the 
mission of the Isotope Program (IP), which in important aspects is 
determined by Congressional direction to both the Office of
Science (SC) and the NNSA, and is not open to interpretation. To 
clarify the roles of both SC and NNSA regarding isotope production, in 
2009, Deputy Secretary of Energy Dan Poneman directed SC and NNSA to 
develop a joint statement, describing the Department's approach to 
isotope research, development, and production to minimize risk or 
misuse. As a result. since the FY 2011 Congressional Budget request 
the Department has included a joint SC/NNSA statement on 
responsibility for isotopes in the SC budget Overview. A copy of the 
statement in the FY 2012 Budget Request is enclosed. While the IP has 
the mission to produce and distribute isotopes that are not 
commercially available and can distribute legacy materials as a 
service to the Department, it does not have the mission to be the 
steward of stockpiles of legacy materials and their byproducts. We 
believe the report, as written, may mislead the reader with an 
impression of the IP's mission and role as related to He-3. 

Below are a couple of points that we feel need some clarification: 

* Throughout the report, the GAO says that NNSA "produces" He-3. NNSA 
does not produce He-3; rather He-3 is extracted. While this may seem 
an issue of semantics, we feel it is important to note that we never 
manufactured He-3 for the purpose of commercial sales. Rather, NNSA 
extracted He-3 as part of our mission to maintain the U.S. nuclear 
weapons stockpile. Additionally, on Page 5 of the report states that
He-3 is rare because it is only produced through the radioactive decay 
of tritium. While He-3 is currently only extracted from the 
radioactive decay of tritium it exists in very low concentration in 
natural sources, for example natural gas. 

* With respect to using Lithium 6 (Li-6) as an alternative technology, 
we are fully aware of the need to avoid incurring the same issues with 
the U.S. Li-6 supply. We have taken steps to evaluate the potential 
demand using the most conservative estimates for Li-6. Should the 
decision be made to use Li-6, we will take all necessary steps to 
ensure there is an adequate supply to meet demand. 

Further, as a result of the Team's discussions, and a Workshop held in 
August 2008 on the Isotope Program's initiative, the supply of other 
isotopes which are sold by the Isotope Program, but produced 
elsewhere, such as Li-6 mentioned in the report, is being addressed.
In the case of Li-6, for example, Portal Monitor users within the USG 
were asked to estimate their long term needs, assuming that all their 
monitors would use Li-6 rather than He-3. As a result of that 
discussion, a Li-6 stockpile has been established to ensure supply of 
Li-6 for Portal Monitor use. We would be happy to provide GAO with 
documents showing our work in this area. 

Also enclosed are specific comments to help clarify and improve the 
report in areas that may be confusing or misleading. 

If you have any questions concerning this response, please contact 
JoAnne Parker, Director, Office of Internal Controls, at 202-586-1913. 

Sincerely, 

Signed by: 

Gerald L. Talbot, Jr. 
Associate Administrator for Management and Budget: 

Enclosures: 

[End of section] 

Appendix II: GAO Contacts and Staff Acknowledgments: 

GAO Contacts: 

Gene Aloise, (202) 512-3841 or aloisee@gao.gov Timothy M. Persons, 
(202) 512-6412 or personst@gao.gov: 

Staff Acknowledgment: 

In addition to the contact named above, Ned H. Woodward, Assistant 
Director; Eric Bachhuber; R. Scott Fletcher; and Wyatt R. Hundrup made 
key contributions to this report. Kendall Childers, Nancy Crothers, 
Cindy Gilbert, Jonathan Kucskar, and Mehrzad Nadji also made important 
contributions. 

[End of section] 

Footnotes: 

[1] Tritium radioactively decays into helium-3 at an annual rate of 
5.5 percent. For further information about tritium production, please 
see GAO, Nuclear Weapons: National Nuclear Security Administration 
Needs to Ensure Continued Availability of Tritium for the Weapons 
Stockpile, [hyperlink, http://www.gao.gov/products/GAO-11-100] 
(Washington, D.C.: October 7, 2010). 

[2] Congress created NNSA as a semiautonomous agency within DOE under 
title 32 of the National Defense Authorization Act for Fiscal Year 
2000 (Pub. L. No. 106-65, § 3211, 113 Stat. 957 (1999)). NNSA is 
responsible for the management and security of the nation's nuclear 
weapons, nonproliferation, and naval reactors programs. 

[3] The Isotope Program did not sell helium-3 from about 1995 through 
2001 because helium-3 was being stockpiled for use in NNSA's 
Accelerator Production of Tritium project. During this time, Russia 
was the primary source of commercially available helium-3. 

[4] Isotopes are chemical elements or varieties of a given chemical 
element with the same number of protons but different numbers of 
neutrons (e.g., helium-3 has one less neutron than helium-4, the 
helium isotope that is commonly used in party balloons). 

[5] Linde acquired Spectra Gases, one of the principal buyers of 
helium-3, in 2006; Spectra Gases changed its name to Linde in 2009. 

[6] GAO, Standards for Internal Control in the Federal Government, 
[hyperlink, http://www.gao.gov/products/GAO/AIMD-00-21.3.1] ("Green 
Book") (Washington, D.C.: November 1999). 

[7] The National Security Staff, established under the National 
Security Advisor, support all White House policymaking activities 
related to international and homeland security matters. 

[8] Chronic obstructive pulmonary disease, commonly referred to as 
COPD, is a lung disease in which the lungs are partially blocked, 
making it difficult to breathe. In this type of research, a patient 
inhales helium-3 during the MRI so that doctors may get a clear view 
of the entire pulmonary structure. 

[9] DOE, Workshop on the Nation's Needs for Isotopes: Present and 
Future, DOE/SC-0107 (Rockville, Maryland, December 2008). 

[10] [hyperlink, http://www.gao.gov/products/GAO/AIMD-00-21.3.1]. 

[11] Nuclear Science Advisory Committee, NSAC Isotopes Subcommittee, 
Isotopes for the Nation's Future: A Long Range Plan. Final Report: 
Second of Two NSAC Charges on the Isotope Development and Production 
and Research for Applications Program (August 27, 2009). 

[12] Current good manufacturing practices (cGMP) are regulations set 
by the Food and Drug Administration for the manufacture of drugs, 
medical devices, and other products to ensure that companies' products 
meet specific requirements for identity, strength, quality, and purity. 

[13] From 2003 through 2009, before helium-3 allocations were managed 
by the policy committee, the price for helium-3 ranged from about $40 
per liter to about $85 per liter. 

[14] Heavy-water reactors are nuclear power reactors that use water 
containing deuterium oxide as a coolant and natural (not enriched) 
uranium as its fuel source. 

[15] We are currently conducting a technology assessment of 
alternatives for detecting neutrons. This technology assessment will 
examine the potential and maturity of various technologies that could 
lower demand for helium-3. We expect to issue a report on this 
assessment later in 2011. 

[End of section] 

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